About Help FAQ

Symbol
Name
ID

Vhl
von Hippel-Lindau tumor suppressor
MGI:103223

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Diabetes mellitus	Pancreatic cysts	Exocrine pancreatic insufficiency	Neoplasm of the pancreas	Pancreatic adenocarcinoma	Elevated circulating erythropoietin concentration	Paraganglioma	Pheochromocytoma
Disease(s) Associated with VHL	Diabetes mellitus	Pancreatic cysts	Exocrine pancreatic insufficiency	Neoplasm of the pancreas	Pancreatic adenocarcinoma	Elevated circulating erythropoietin concentration	Paraganglioma	Pheochromocytoma
familial erythrocytosis 2
pancreatic cancer
pheochromocytoma
von Hippel-Lindau disease

Mouse Phenotypes		abnormal exocrine pancreas morphology	endocrine/exocrine gland phenotype	abnormal pancreatic islet morphology	pancreas cyst	decreased Sertoli cell number	seminiferous tubule degeneration	small testis	increased pancreas adenoma incidence
Availability	Mouse Genotype	abnormal exocrine pancreas morphology	endocrine/exocrine gland phenotype	abnormal pancreatic islet morphology	pancreas cyst	decreased Sertoli cell number	seminiferous tubule degeneration	small testis	increased pancreas adenoma incidence
	Vhl^tm1Lss/Vhl^tm1Lss Tg(Gcg-cre)1Slib/0 (conditional)		*
	Vhl^tm1Lss/Vhl^tm1Lss Tg(Ins2-cre)25Mgn/0 (conditional)		*
	Vhl^tm1Lss/Vhl^tm1Lss Tg(Pdx1-cre)89.1Dam/0 (conditional)
	Vhl^tm1Lss/Vhl^tm1.1Lss Tg(ACTB-cre)1Tes/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23